Evaluation of Non-Invasive Gargle Lavage Sampling for the Detection of SARS-CoV-2 Using rRT-PCR or Antigen AssayArticle Published on 2022-12-192023-07-11 Journal: Viruses [Category] COVID19(2023년), [키워드] Antigen assay gargle lavage Non-invasive PCR SARS-CoV-2 self-sampling. [DOI] 10.3390/v14122829 PMC 바로가기
Evaluation of qualitative and semi-quantitative cut offs for rapid diagnostic lateral flow test in relation to serology for the detection of SARS-CoV-2 antibodies: findings of a prospective studyArticle Published on 2022-10-312022-11-15 Journal: BMC Infectious Diseases [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] 95% CI Accuracy acute respiratory syndrome Analysis antibodies antibody Antibody detection assessments Blood capillary blood chemiluminescent immunoassay CLIA coronavirus coronavirus disease COVID-19 COVID-19 disease cut off cut-off Diagnosis diagnosis of COVID-19 diagnostic Efficacy ELISA evaluate facilitate gold standard identify IgM and IgG immunochromatographic assay information intensity Italy Laboratory Lateral lateral flow lateral flow immunoassay Lateral flow test measure NAAT Non-invasive nucleic acid amplification Patient patients performed POC positive Prospective Study provided Quantitative Rapid Rapid diagnostic test RDT SARS-CoV-2 SARS-CoV-2 antibody semi-quantitative sensitivity serological test serology Serology. Severity of disease specificity symptom onset Test the timing venous whole sample [DOI] 10.1186/s12879-022-07786-5 PMC 바로가기
Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19Research article Published on 2022-10-012022-10-05 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), SARS, 바이오마커, 변종, 유전자 메커니즘, 임상, 진단, 치료기술, [키워드] 95% CI Activation adjusted adjusted odds ratio aggregation Alpha Analysis application B.1.1.7 Bath biochemical Biomarkers biomarkers of inflammation biopsy changes clinical factors clinical outcomes clinically Coagulation Cohort Complication correlation Council COVID-19 death develop Dexamethasone diagnostic Direct driving dysregulation of coagulation Engineering evaluated facilitate finding foundation funding hazard ratio heart hospital identify in-hospital mortality indicated Inflammation investigated mammary marker myocardial injury National Health Service NHS NIHR Non-invasive outcome Oxford parameters Pathways Patient patients with COVID-19 perivascular Platelet platform predict produced Prognostic value pulmonary angiography pulmonary CT representing respond responsible risk RNA sequencing data SARS-CoV-2 variant Science sensitivity analysis targeted therapy therapeutic target transcriptional transcriptomic Treatment Trial validation study variant vascular inflammation Wellcome Trust Whole blood wild-type SARS-CoV-2 with COVID-19 [DOI] 10.1016/S2589-7500(22)00132-7 [Article Type] Research article
Clinical studies of detecting COVID-19 from exhaled breath with electronic noseArticle Published on 2022-09-262022-11-15 Journal: Scientific Reports [Category] SARS, 치료기술, [키워드] Accuracy affecting Analysis breath can be used clinical continuous monitoring coronavirus SARS-CoV-2 COVID-19 COVID-19 pandemic detect diagnostic methods exploratory gold standard help hospital limit Local metabolism Non-invasive Numerous pandemic Patient PCR point-of-care test polymerase chain problem reported Research Schools spread of COVID-19 Treatment viral infections virus infection VoC VOCs [DOI] 10.1038/s41598-022-20534-8 PMC 바로가기
Interleukin-17, a salivary biomarker for COVID-19 severityArticle Published on 2022-09-222022-11-15 Journal: PLoS ONE [Category] SARS, 바이오마커, [키워드] acute respiratory syndrome Admission adult COVID-19 patient Biomarker Blood C-reactive protein can be used cell-mediated response Comorbidity coronavirus COVID-19 COVID-19 disease severity COVID-19 patient COVID-19 severity cytokine death demographics determine disease severity ELISA evaluated ferritin identify IL-17 Infection interleukin-17 marker mechanical ventilation Non-invasive Patient reflected risk Saliva salivary SARS-CoV-2 serum severe COVID-19 severe COVID-19 patients severity with COVID-19 [DOI] 10.1371/journal.pone.0274841 PMC 바로가기
Untargeted saliva metabolomics by liquid chromatography-Mass spectrometry reveals markers of COVID-19 severityArticle Published on 2022-09-222022-11-15 Journal: PLoS ONE [Category] 바이오마커, 변종, [키워드] Amino acid amino acids analysed Analysis C-reactive protein Clinical diagnosis Clinical severity clinical suspicion Clinical tests collected COVID-19 COVID-19 diagnosis COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 severity Diagnosis diagnostic Disease progression driver dysregulation eliminating expand exploratory feature Health hospital hospitalised patient likelihood marker metabolomics Metadata Non-invasive offer outcomes Patient patients peripheral oxygen saturation Prognosis progressed receiver operating characteristics recent Research reservoir respiratory rate resulting reveal RT-PCR testing Saliva saliva sample serum severity shown the disease Treatment Vaccine variants [DOI] 10.1371/journal.pone.0274967 PMC 바로가기
Differences in systemic and mucosal SARS-CoV-2 antibody prevalence in a prospective cohort of Dutch childrenArticle Published on 2022-09-092022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] 95% CI affected antibodies antibody antibody assay Antibody assays Antibody prevalence association children clinical variables cohort study Concordance cross-sectional Demographic variables difference evaluate healthy children Humoral immunity IgA IgG IgG positivity Immunity Immunocompromised infected children Infection investigated medical service MONITOR mucosal mucosal antibody response mucosal IgG Netherland Non-invasive performed positive Prevalence prospective cohort RBD RBD-specific IgG Receptor binding domain reduced Saliva saliva antibodies. SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 spike serum Sex Symptom vaccination [DOI] 10.3389/fimmu.2022.976382 PMC 바로가기
SARS-CoV-2 Spike and Nucleocapsid Antibody Response in Vaccinated Croatian Healthcare Workers and Infected Hospitalized Patients: A Single Center Cohort StudyArticle Published on 2022-09-042022-11-15 Journal: Viruses [Category] SARS, 변종, 진단, 치료기술, [키워드] antibodies binding antibody Antibody detection Antibody Response BNT162 vaccine center clinical Cohort cohort of patient contribute correlated COVID-19 COVID-19 patient COVID-19 patients COVID-19 vaccine Critically ill Critically ill patient decrease disease ELISA assay group HCW HCWs health-care healthcare Healthcare workers hospitalized patients hospitalized patients. Humoral response invasive ventilation management Non-invasive nucleocapsid omicron outcome oxygen supplementation Pandemics Protein response Rijeka risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant Seroconversion significant difference significantly spike Spread Support sustained tested vaccination vaccination schedule vaccinee VoC VOCs worker [DOI] 10.3390/v14091966 PMC 바로가기
Follow-up evaluation of patients with liver test abnormalities detected during SARS-CoV2 infectionSARS-CoV2 감염 중 간검사 이상 소견이 발견된 환자에 대한 추적조사Observational Study Published on 2022-09-012022-09-11 Journal: Journal of viral hepatitis [Category] COVID19(2023년), SARS, 임상, 치료기술, [키워드] Abnormalities abnormality Admission antibiotic Blood blood test coronavirus disease Coronavirus disease-19 COVID-19 criteria defined discharge disease during admission evaluated Evolution Factor Fatty liver fatty liver disease ferritin Follow-up Gender immunomodulatory individuals Infection inspired oxygen fraction liver Liver Biopsy Liver function Liver function test liver function tests male metabolic-associated fatty liver disease (MAFLD). Most patient Most patients no correlation Non-invasive observational study outcome oxygen P/F partial pressure Partial pressure of oxygen Patient patients persistent Retrospective analysis SARS-CoV2 SARS-CoV2 infection severity Treatment variable was performed [DOI] 10.1111/jvh.13718 PMC 바로가기 [Article Type] Observational Study
A non-invasive ultrasensitive diagnostic approach for COVID-19 infection using salivary label-free SERS fingerprinting and artificial intelligenceResearch article Published on 2022-09-012022-10-05 Journal: Journal of photochemistry and photobiology. B, Bio [Category] SARS, 바이오마커, 변종, 진단, 치료기술, [키워드] Accuracy approach artificial intelligence biochemical change Classifier clinical COVID-19 COVID-19 infected patient COVID-19 infection COVID-19 outbreak demonstrated Diagnosis diagnostic diagnostics Efficiency false-negative genetic diversity global healthcare gold standard healthy healthy control high accuracy invasive Label-free limit Machine learning algorithms management MERS-CoV Mutation Nasopharyngeal swab Non-invasive Patient Population screening positive predicted reagents risk Saliva salivary SARS-CoV SARS-CoV-2 SARS-COV-2 infection scattering sensitivity specificity Stage subjects Support surface enhanced Raman spectroscopy SVM the patient virus virus spike protein [DOI] 10.1016/j.jphotobiol.2022.112545 [Article Type] Research article